Pathogen identification in nosocomial pneumonia is often problematic1,2

When treating HABP and VABP, it may be necessary to prescribe an antibiotic with limited pathogen information due to difficulties in1,2:

Obtaining samples and low sensitivity of testing methods
Differentiating between respiratory tract colonization and infection

Treatment for HABP and VABP is often administered on the basis of1:

Previous antibiotic exposure
Patient-specific factors such as prior culture results and antimicrobial resistance patterns
Hospital antibiogram
Length of hospitalization prior to the occurrence of HABP/VABP